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By bridging epidemiological evidence with mechanistic insights, this work advances our understanding of how cigarette smoke interacts with genetic regulators to affect immune responses and sheds new light on the complexity and heterogeneity underlying IBD pathogenesis

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They are also more likely to be around other smokers, normalising the behaviour and making it harder to quit successfully

Miscarriage and preterm birth Smoking heightens the risk of miscarriage, where a pregnancy is lost before it reaches viability